Table 3.

Cox regression analysis of the inflammatory markers‐based cachexia.

Categories	Model a (HR, 95% CI)	P value	Model b (HR, 95% CI)	P value	Model c (HR, 95% CI)	P value
NLR‐based cachexia	1.836 (1.689, 1.996)	<0.001	1.489 (1.356, 1.634)	<0.001	1.481 (1.348, 1.627)	<0.001
IBI‐based cachexia	1.922 (1.768, 2.09)	<0.001	1.534 (1.397, 1.683)	<0.001	1.504 (1.37, 1.652)	<0.001
ALB‐based cachexia	1.874 (1.724, 2.037)	<0.001	1.525 (1.389, 1.675)	<0.001	1.526 (1.39, 1.676)	<0.001
GPS‐based cachexia	1.858 (1.709, 2.019)	<0.001	1.493 (1.36, 1.638)	<0.001	1.473 (1.341, 1.619)	<0.001

Note: Model a: Not adjusted. Model b: Adjusted for age, sex, BMI, TNM stage. Model c: Adjusted for age, sex, BMI, TNM stage, tumour type, surgery, radiotherapy, chemotherapy, hypertension, diabetes, coronary heart disease, smoking, drinking and family history.

Abbreviations: ALB, albumin; CI, confidence interval; GPS, Glasgow prognostic score; HR, hazard ratio; IBI, inflammatory burden index; NLR, neutrophil‐to‐lymphocyte ratio.