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. 2024 Oct 2;10(6):e70004. doi: 10.1002/2056-4538.70004

Table 1.

Details of cohort

Clinical characteristics AJMC (n = 197) HUMC (n = 145) CNUH (n = 397) INHA (n = 129)
EGFR wild‐type (n = 69) EGFR mutant (n = 128) p EGFR wild‐type (n = 80) EGFR mutant (n = 65) p EGFR wild‐type (n = 235) EGFR mutant (n = 162) p EGFR wild‐type (n = 67) EGFR mutant (n = 62) p
Gender Female 26 85 0.0001 29 41 0.0023 85 104 0.0001 24 45 0.0001
Male 43 43 51 24 150 58 43 17
Smoking status Y 52 107 0.2272 53 53 0.0605 97 92 0.0032 32 51 0.0001
N 17 21 27 12 128 70 35 11
Family history Y 66 126 0.477 74 59 0.736 209 128 0.0101 49 46 0.9493
N 3 2 5 6 26 34 18 16
Age (mean) 66.09 ± 9.94 64.10 ± 9.78 0.0941 65.15 ± 11.07 66.34 ± 12.51 0.3934 67.19 ± 9.34 66.37 ± 9.433 0.1505 63.17 ± 10.94 62.98 ± 12.01 0.4727
Height (mean) 162.69 ± 8.09 158.78 ± 9.15 0.0007 161.40 ± 8.51 159.21 ± 7.33 0.0404 162.01 ± 8.73 158.65 ± 8.28 0.0001 163.17 ± 7.07 157.89 ± 7.85 0.0003
Weight (mean) 62.85 ± 10.68 59.37 ± 10.93 0.0195 62.84 ± 10.67 59.58 ± 9.51 0.0334 64.50 ± 10.32 60.77 ± 10.24 0.0001 65.04 ± 11.64 62.23 ± 9.39 0.1813
Stage I 44 101 0.0832 46 41 0.2866 189 133 0.3522 41 46 0.2664
II 11 14 7 7 26 18 8 8
III 11 8 12 12 10 2 16 7
IV 3 5 15 5 10 9 2 1

The clinicopathological characteristics of cohorts of lung adenocarcinoma patients collected from four institutions, AJMC, HUMC, CNUH, and INHA, are summarized according to EGFR mutations. The statistical significance of differences between groups was evaluated by the chi‐square test or t‐test.