Table 1.
Clinical characteristics | AJMC (n = 197) | HUMC (n = 145) | CNUH (n = 397) | INHA (n = 129) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
EGFR wild‐type (n = 69) | EGFR mutant (n = 128) | p | EGFR wild‐type (n = 80) | EGFR mutant (n = 65) | p | EGFR wild‐type (n = 235) | EGFR mutant (n = 162) | p | EGFR wild‐type (n = 67) | EGFR mutant (n = 62) | p | ||
Gender | Female | 26 | 85 | 0.0001 | 29 | 41 | 0.0023 | 85 | 104 | 0.0001 | 24 | 45 | 0.0001 |
Male | 43 | 43 | 51 | 24 | 150 | 58 | 43 | 17 | |||||
Smoking status | Y | 52 | 107 | 0.2272 | 53 | 53 | 0.0605 | 97 | 92 | 0.0032 | 32 | 51 | 0.0001 |
N | 17 | 21 | 27 | 12 | 128 | 70 | 35 | 11 | |||||
Family history | Y | 66 | 126 | 0.477 | 74 | 59 | 0.736 | 209 | 128 | 0.0101 | 49 | 46 | 0.9493 |
N | 3 | 2 | 5 | 6 | 26 | 34 | 18 | 16 | |||||
Age (mean) | 66.09 ± 9.94 | 64.10 ± 9.78 | 0.0941 | 65.15 ± 11.07 | 66.34 ± 12.51 | 0.3934 | 67.19 ± 9.34 | 66.37 ± 9.433 | 0.1505 | 63.17 ± 10.94 | 62.98 ± 12.01 | 0.4727 | |
Height (mean) | 162.69 ± 8.09 | 158.78 ± 9.15 | 0.0007 | 161.40 ± 8.51 | 159.21 ± 7.33 | 0.0404 | 162.01 ± 8.73 | 158.65 ± 8.28 | 0.0001 | 163.17 ± 7.07 | 157.89 ± 7.85 | 0.0003 | |
Weight (mean) | 62.85 ± 10.68 | 59.37 ± 10.93 | 0.0195 | 62.84 ± 10.67 | 59.58 ± 9.51 | 0.0334 | 64.50 ± 10.32 | 60.77 ± 10.24 | 0.0001 | 65.04 ± 11.64 | 62.23 ± 9.39 | 0.1813 | |
Stage | I | 44 | 101 | 0.0832 | 46 | 41 | 0.2866 | 189 | 133 | 0.3522 | 41 | 46 | 0.2664 |
II | 11 | 14 | 7 | 7 | 26 | 18 | 8 | 8 | |||||
III | 11 | 8 | 12 | 12 | 10 | 2 | 16 | 7 | |||||
IV | 3 | 5 | 15 | 5 | 10 | 9 | 2 | 1 |
The clinicopathological characteristics of cohorts of lung adenocarcinoma patients collected from four institutions, AJMC, HUMC, CNUH, and INHA, are summarized according to EGFR mutations. The statistical significance of differences between groups was evaluated by the chi‐square test or t‐test.