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. 2024 Sep 19;14:1388991. doi: 10.3389/fcimb.2024.1388991

Table 1.

Clinical features of Patients with PTB and CAP.

features All Cohort Training Cohort Testing Cohort Validation Cohort
CAP PTB CAP PTB CAP PTB CAP PTB
n 163 195 74 96 32 41 58 57
Sex (%)
Female 86 (24%) 79 (22.1%) 45 (26.5%) 40 (23.5%) 12 (16.4%) 11 (15.1%) 30 (26.1%) 28 (24.3%)
Male 77 (21.5%) 116 (32.4%) 29 (17.1%) 56 (32.9%) 20 (27.4%) 30 (41.1%) 28 (24.3%) 29 (25.2%)
Age 51 (31, 67) 61 (46, 71.5) 49 (30.25, 66) 62 (41, 73) 52 (35.75, 66.25) 64 (49, 70) 60 (42.25, 69.75) 52 (31, 67)
WBC 6.26 (4.93, 8.20) 7.19 (5.54, 9.36) 6.26 (4.51, 8.70) 7.20 (5.57, 9.35) 5.97 (5, 7.44) 6.92 (4.99, 8.97) 7.64 ± 2.92 7.12 ± 2.88
NEUT% 64.2 (55.8, 74.75) 72.64 (63.95, 81.01) 64.49 ± 14.63 71.38 ± 11.92 64.32 ± 12.17 72.81 ± 11.96 72.26 ± 10.70 66.53 ± 14.73
LYMPH% 25.8 (16.35, 32.15) 15.54 (11.4, 24.75) 24.9 (16.16, 35.06) 16.5 (11.65, 24.88) 27.3 (20.49, 31.83) 14.9 (8.8, 24.7) 15.52 (11.55, 24.48) 23.5 (14.84, 31)
HGB 122 (110.5, 134) 114 (100.5, 125) 120.5 (111, 131) 114.5 (101, 126.25) 125.47 ± 16.629 114.12 ± 20.44 113 (98, 122.5) 124 (110, 134)
PLT 217 (183, 290) 247 (204.5, 334) 215.5 (174.25, 290) 233.5 (195.5, 318.25) 218.56 ± 56.786 288.9 ± 126.4 254 (221, 337.75) 235 (196, 303)
ALB 37.93 ± 6.17 34.86 ± 5.63 38.51 ± 6.01 35.11 ± 5.18 38.4 (34.28, 41.53) 33.9 (30.4, 37.9) 35.10 ± 5.81 37.37 ± 6.48
GLU 5.33 (4.73, 6.04) 5.06 (4.56, 5.79) 5.33 (4.65, 6.14) 4.985 (4.54, 5.54) 5.21 (4.76, 5.77) 5.12 (4.56, 6.13) 5.09 (4.6, 5.76) 5.41 (4.97, 6.17)
CRP 22.1 (2.81, 76.89) 28.2 (7.45, 70.05) 18.19 (2.98, 66.04) 28.78 (6.30, 54.83) 16.4 (1.35, 61.36) 24.4 (7.4, 77.7) 28.64 (9.5, 71.95) 36.1 (3.44, 83.1)
T-SPOT, (%)
negative 129 (36%) 42 (11.7%) 62 (36.5%) 19 (11.2%) 23 (31.5%) 7 (9.6%) 16 (13.9%) 44 (38.3%)
Positive 34 (9.5%) 153 (42.7%) 12 (7.1%) 77 (45.3%) 9 (12.3%) 34 (46.6%) 42 (36.5%) 13 (11.3%)
Fever, (%)
≥37.3°C 122 (34.1%) 67 (18.7%) 53 (31.2%) 35 (20.6%) 26 (35.6%) 10 (13.7%) 36 (31.3%) 14 (12.2%)
<37.3°C 41 (11.5%) 128 (35.8%) 21 (12.4%) 61 (35.9%) 6 (8.2%) 31 (42.5%) 22 (19.1%) 43 (37.4%)
Cough,(%)
Yes 139 (38.8%) 163 (45.5%) 12 (7.1%) 17 (10%) 26 (35.6%) 35 (47.9%) 9 (7.8%) 6 (5.2%)
No 24 (6.7%) 32 (8.9%) 62 (36.5%) 79 (46.5%) 6 (8.2%) 6 (8.2%) 49 (42.6%) 51 (44.3%)
Expectoration,(%)
Yes 109 (30.4%) 151 (42.2%) 25 (14.7%) 23 (13.5%) 20 (27.4%) 30 (41.1%) 10 (8.7%) 17 (14.8%)
No 54 (15.1%) 44 (12.3%) 49 (28.8%) 73 (42.9%) 12 (16.4%) 11 (15.1%) 48 (41.7%) 40 (34.8%)
Hemoptysis,(%)
No 132 (36.9%) 140 (39.1%) 61 (35.9%) 69 (40.6%) 22 (30.1%) 32 (43.8%) 39 (33.9%) 49 (42.6%)
Yes 31 (8.7%) 55 (15.4%) 13 (7.6%) 27 (15.9%) 10 (13.7%) 9 (12.3%) 19 (16.5%) 8 (7%)

The data of normal distribution were described as mean ± standard deviation (SD) compared by t test. Data that are not normally distributed were expressed as median (range interquartile) and analyzed using the rank-sum test.

WBC, white blood cell count; NEUT%, neutrophil ratio; LYMPH%, neutrophil to lymphocyte ratio; CRP, C-reactive protein; HGB, Hemoglobin; PLT, platelets; ALB, albumin; GLU, glucose.