Table 3.
Performance of the Clinical Model, Radiomics Model, and Clinical Model in the Training Cohort, Test Cohort and validation Cohort.
| Different Models | AUC | SEN | SPE | ACC | F1 | PPV | NPV | FNR | FDR | FPR | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Radiomics Model | Train Cohort | 0.887 | 0.885 | 0.716 | 0.812 | 0.842 | 0.802 | 0.828 | 0.115 | 0.198 | 0.284 |
| Test Cohort | 0.787 | 0.756 | 0.563 | 0.671 | 0.721 | 0.689 | 0.643 | 0.244 | 0.311 | 0.438 | |
| Validation Cohort | 0.793 | 0.776 | 0.649 | 0.713 | 0.732 | 0.692 | 0.740 | 0.224 | 0.308 | 0.351 | |
| Clinical Model | Train Cohort | 0.855 | 0.802 | 0.838 | 0.818 | 0.832 | 0.865 | 0.765 | 0.198 | 0.135 | 0.162 |
| Test Cohort | 0.827 | 0.805 | 0.719 | 0.767 | 0.795 | 0.786 | 0.742 | 0.195 | 0.214 | 0.281 | |
| Validation Cohort | 0.799 | 0.707 | 0.772 | 0.739 | 0.732 | 0.759 | 0.721 | 0.293 | 0.241 | 0.228 | |
| Conjoint Model | Train Cohort | 0.948 | 0.875 | 0.892 | 0.882 | 0.894 | 0.913 | 0.846 | 0.125 | 0.087 | 0.108 |
| Test Cohort | 0.888 | 0.805 | 0.844 | 0.822 | 0.835 | 0.868 | 0.771 | 0.195 | 0.132 | 0.156 | |
| Validation Cohort | 0.850 | 0.759 | 0.825 | 0.791 | 0.786 | 0.815 | 0.771 | 0.241 | 0.185 | 0.175 |
AUC, the area under the curve; SEN, sensitivity; SPE, specificity; ACC, accuracy; PPV, Positive predictive value; NPV, Negative predictive value; FNR, False negative rate; FDR, False discovery rate; FPR, False positives rate.