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. 2024 Sep 2;56(9):1980–1990. doi: 10.1038/s12276-024-01298-9

Fig. 7. Model showing the role of STAT3 in NLRP3 inflammasome activation.

Fig. 7

STAT3 promotes NLRP3 inflammasome activation by mediating NLRP3 mitochondrial translocation, and this process is inhibited by napabucasin through disruption of the interaction between STAT3 and NLRP3.