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. 2024 Oct 2;14:22917. doi: 10.1038/s41598-024-74287-7

Table 4.

Adjusted risk of CAC according to the subgroups of different steatotic liver statuses.

Number Presence of CAC Model 1
aOR (95% CI)
Model 2
aOR (95% CI)
Model 3
aOR (95% CI)
Neither MASLD nor MAFLD 1466 482 1 (ref.) 1 (ref.) 1 (ref.)
MASLD only 54 21 1.30 (0.73–2.25) 1.30 (0.73–2.25) 1.30 (0.73–2.25)
MAFLD only 402 182 1.45 (1.13–1.86)* 1.29 (0.99–1.67) 1.11 (0.86–1.43)
Both MASLD and MAFLD 851 375 1.48 (1.22–1.81)* 1.34 (1.09–1.64)* 1.22 (1.01–1.47)*

*A p-value < 0.05. Model 1, adjusted for age and sex; Model 2, Model 1 + smoking, use of statins, diabetes, and advanced fibrosis; Model 3: ASCVD risk score. Presence of CAC is defined as a CAC score > 0 and advanced fibrosis is defined as a fibrosis-4 index ≥ 2.67. The ASCVD risk score includes age, sex, race, smoking status, blood pressure, medication use for hypertension, diabetes status, total cholesterol, and high-density lipoprotein cholesterol. CAC coronary artery calcification, aOR adjusted odds ratio, CI confidence interval, MASLD metabolic dysfunction-associated steatotic liver disease, MAFLD metabolic dysfunction-associated fatty liver disease, ref. reference.