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. 2024 Aug 28;39(10):2297–2304. doi: 10.1093/humrep/deae191

Table 2.

Effects of cryostorage-related anxiety on perceived stress and somatic symptom severity.

Cryostorage-related anxiety levels The UK survey
The US survey
PSS change (95% CI) PHQ-15 change (95% CI) PSS change (95% CI) PHQ-15 change (95% CI)
None Ref Ref Ref Ref
Mild 3.89 (0.85–6.94) 3.25 (0.57–5.92) 2.49 (0.02–4.97) 1.96 (−0.34 to 4.25)
Moderate 7.60 (4.29–10.9) 5.25 (2.35–8.16) 5.73 (3.23–8.26) 4.02 (1.70–6.34)
High 10.7 (7.15–14.2) 5.48 (2.37–8.59) 5.24 (2.57–7.91) 5.43 (2.96–7.91)
Constant 18.9 (12.2–25.7) 7.76 (1.83–13.7) 6.44 (3.28–9.60) 5.17 (2.24–8.11)

Change and 95% CI in Perceived Stress Scale (PSS) and Patient Health Questionnaire (PHQ)-15 scores adjusted for the following variables: years as an embryologist, full-time vs part-time/per-diem working status, and doctorate-level education. Bold denotes a statistically significant dose-dependent effect of cryostorage-related anxiety on PSS and PHQ-15 changes.