Table I.
Demographic and clinical characteristics of the reviewed cohort
Authors | Ref | Patient | Gender | Age (years) | Smoking history (Y/N) | Tumour site | Tumour size (cm) | Lymphnode metastasis (Y/N) | Site of distant metastasis | cTNM staging1 | Treatment | Follow up/Months | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Yoshida K, Fujiwara Y, et al. | 23 | 1 | F | 33 | N | Left pleura | Multiple tumours | N | None | cTxN0M0 | Adjuvant CT | DOD/10 | |
Haberecker M, Buhler MM, et al. | 24 | 2 | F | 20 | N | Anterior mediastinum | ~4 | N | Bone, lung3, soft tissue and nerve plexus | cTxN0M1c | Adjuvant CT | DOD/16 | |
3 | M | 25 | Y | Pleura/thoracic wall, axilla | 15,8 | Y | Pleura | cT4N2M1a | Adjuvant CT | DOD/17 | |||
4 | M | 51 | Y | Lung, central/hilar | 4-5 | Y | Pleura | cT2bN2M1a | Adjuvant CT | DOD/6 | |||
5 | M | 56 | Y | Pleura | -2 | N | None | cTxN0M0 | Adjuvant CT | DOD/1 | |||
6 | M | 76 | NA | Lung, subpleural | 3,5 | N | NA | cT2aN0M0 | NA | NA/2 | |||
7 | M | 73 | Y | Lung, central/hilar | 5 | Y | Liver, adrenal gland | cT2bN2M1c | Neoadjuvant and adjuvant CT | DOD/7 | |||
8 | M | 64 | Y | Pleura | -2 | N | None | cT3N0M0 | Adjuvant CT | DOD/10 | |||
9 | M | 72 | Y | Lung, central/hilar | 9 | N | Lung3 | cT4N0M1a | Adjuvant CT | DOD/53 | |||
10 | M | 77 | N | Posterior mediastinum/esophagus | 10 | N | None | cT4N0M0 | Neoadjuvant CT | DOD/4 | |||
Zhou YH, Qin S, et al. | 25 | 11 | M | 74 | NA | Lung, RUL | 3,5 | N | None | cT2NcMx | Neoadjuvant RT | DOD/5+4 | |
Rickard JA, Burr M, et al. | 26 | 12 | M | 60s5 | N | Lung, LLL | 8,6 | Y | Liver | cT4N2M1c | Neoadjuvant CT | AWD | |
Chen J, Wang J | 27 | 13 | M | 61 | N | Lung, LUL | 8,8 | Y | None | cT4N2M0 | Neoadjuvant and adjuvant CT | NED/4+6 | |
Present case | - | 14 | M | 38 | N | Lung, RML | 5,8 | N | None | cT3N0M0 | Neoadjuvant CT | DOD/11 | |
1 according to the available data, 2 entire lateral parietal pleura, 3 data regarding precise location not available, 4 patient was alive with disease after 5 months of radiotherapic treatment and died of disease after therapeutic failure (interval is not reported in the original article), 5 in the original article, the authors report that the patient is in his sixties with no further clarification, 6 in the original article, no further clarification is given on the follow-up time | |||||||||||||
AWD alive with disease, CT chemotherapy treatment, DOD died of disease, IHC immunohistochemistry, LLL left lower lobe, LUL left upper lobe, NA not available, NED no evidence of disease, RML right middle lobe, RUL right upper lobe |