Table 3. Antibacterial Activity of Compounds 1–3, Bromo Benzenediol Derivatives, and Antibiotics.
| MIC (μg/mL) |
||
|---|---|---|
| tested compounds | S. aureus | P. aeruginosa |
| 1 | 24 | 780 |
| 2 | 12 | 780 |
| 3 | 390 | 780 |
| 3-bromo-4-(2,3-dibromo-4,5-dihydroxyphenyl) methyl-5-(hydroxymethyl)-1,2-benzenediol (4)a | 140 | >140 |
| 3-bromo-4-(2,3-dibromo-4,5-dihydroxyphenyl) methyl-5-(ethoxymethyl)-1,2-benzenediol (5)a | 70 | >140 |
| 3-bromo-4-(2,3-dibromo-4,5-dihydroxyphenyl) methyl-5-(methoxymethyl)-1,2-benzenediol (6)a | 70 | >140 |
| 4,4′-methylenebis(5,6-dibromo-1,2-benzenediol) (7)a | 140 | 140 |
| bis(2,3-dibromo-4,5-dihydroxybenzyl)ether (8)a | 70 | 70 |
| ampicillin | 10 | |
| tetracycline | 30 | 70 |
| tobramycin | 25 | 15 |
a
Bromo benzenediol derivatives from the study of Liu et al.7