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. 2024 Sep 17;9(39):40346–40357. doi: 10.1021/acsomega.4c01183

Table 8. Results of Placket–Burmann experimental design.

  ObtainedP Values
R2 Value
Results Wavelength Column Temperature Flow Rate pH Value of Mobile Phase Model Model
Carglumic acid assay (%) 0.415 0.652 0.771 0.951 0.512 0.7812
Related compound A (%) 0.598 0.142 0.598 0.028 0.116 0.6102
Pyrocarglumic acid 0.879 0.197 0.454 0.008 0.054 0.6951
Dicarbamoyll-glutamic acid 1.000 0.104 0.104 0.104 0.125 0.6000
Pyroglutamic acid 0.423 0.785 0.785 0.423 0.802 0.1869
Total impurities 0.415 0.127 0.536 0.415 0.378 0.4134