Table 3. Extraction Recovery and Matrix Effect of HHC and IS in Mice Plasma, Brain, Liver, and Kidney (Mean ± SD, n = 3).

	HHC		IS
tissues (matrix)	accuracy (%)	precision (CV%)	accuracy (%)	precision (CV%)
extraction recovery
plasma	89.62 ± 3.57	3.99	113.74 ± 8.64		7.59
brain	93.28 ± 6.07	6.51	112.24 ± 6.56		5.84
liver	70.18 ± 2.20	3.13	81.23 ± 3.03		3.73
kidney	72.60 ± 5.90	8.12	109.66 ± 6.87		6.26
matrix effect
plasma	92.82 ± 2.75	2.97	121.57 ± 8.32		6.84
brain	105.05 ± 10.73	10.22	117.24 ± 3.20		2.73
liver	77.70 ± 6.32	8.14	103.45 ± 5.30		5.13
kidney	86.50 ± 0.06	0.07	122.63 ± 15.19		12.39