Figure 1. Cumulative burden of A) overall major adverse cardiovascular events (MACE) in survivors of childhood cancer compared with community controls, B) specific MACE conditions in survivors, C) overall non-MACE in survivors compared with community controls, and D) specific non-MACE conditions in survivors; N=9,602 for survivors and N=737 for controls.
Shaded areas represent the 95% confidence interval bands for the estimated cumulative burden per individual.
Panels A and C: p-values for survivors vs. controls curves are <0·0001
