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. 2024 Aug 28;12(10):e00474-24. doi: 10.1128/spectrum.00474-24

TABLE 1.

MIC and MFC values of several antifungals against S. schenckii and S. brasiliensis yeast and mycelial phasesa

CSP
(4–0.06
μg/mL)
VCZ
(4–0.06
μg/mL)
ITZ
(8–0.125
μg/mL)
MFS
(16–0.25
μg/mL)
ML
(16–0.25
μg/mL)
TRB
(4–0.06
μg/mL)
AMB
(8–0.125
μg/mL)
Ss 4820 Y MIC >4 >4 0.25 2 2 1 2
MFC >4 >4 0.5 2 2 1 2
M MIC >4 >4 2 2 2 1 2
MFC >4 >4 >8 2 2 1 2
Ss 4821 Y MIC >4 >4 0.5 2 2 1 2
MFC >4 >4 2 2 2 1 2
M MIC >4 >4 1 2 2 1 2
MFC >4 >4 >8 2 2 1 2
Ss 4822 Y MIC >4 >4 0.125 2 2 0.5 2
MFC >4 >4 0.25 2 2 0.5 2
M MIC >4 >4 2 2 2 1 2
MFC >4 >4 >8 2 2 1 2
Sb 4823 Y MIC >4 >4 2 2 2 0.5 2
MFC >4 >4 >8 2 2 0.5 2
M MIC >4 >4 1 2 2 1 2
MFC >4 >4 >8 2 2 1 2
Sb 4824 Y MIC >4 >4 0.5 2 2 0.5 >8
MFC >4 >4 1 2 2 0.5 >8
M MIC >4 >4 2 2 2 1 2
MFC >4 >4 >8 2 2 1 2
Sb 4858 Y MIC >4 >4 0.125 2 2 0.125 2
MFC >4 >4 2 2 2 0.125 2
M MIC >4 >4 1 2 2 1 2
MFC >4 >4 >8 2 2 1 2
a

Ss: S. schenckii, Sb: S. brasiliensis, Y: yeast phase, M: mycelial phase; CSP: caspofungin, VCZ: voriconazole, ITZ: itraconazole, MFS: miltefosine, ML: milteforan, TRB: terbinafine, AMB: amphotericin B.