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. 2024 Sep 13;12(10):e02831-23. doi: 10.1128/spectrum.02831-23

Fig 3.

ROC curves evaluate diagnostic accuracy of cytokine and biomarker profiles for distinguishing bacterial from viral infections, including SARS-CoV-2. AUC values of 0.98, 0.97, and 0.94 indicate high diagnostic accuracy in all comparisons.

Receiver operator characteristic (ROC) curves for protein signatures that distinguish (A) patients with bacterial from viral etiology, (B) patients with bacterial from viral and SARS-CoV-2 etiology, and (C) patients with bacterial and mixed bacterial–viral etiology (“antibiotics justified”) from patients with viral and SARS-CoV-2 etiology (“antibiotics not justified”).