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. 2024 Sep 12;12(10):e03432-23. doi: 10.1128/spectrum.03432-23

Fig 6.

3D protein structure depicts surface mapping with two highlighted mutations indicating specific locations of interest within the protein complex. Domain structures are color-coded.

The two amino acid substitution sites corresponding to reported neutralizing mAb sites in the HN protein of newly sequenced HPIV3 strains were mapped on the structure model of prototype strain Washington 1957. Template for homology modeling was using the crystal structure of 4xjq. Chains of the dimer structure model were colored in green (chain A) and cyan (chain B). The N461D and K500R amino acid substitution sites were labeled within red and white color, respectively.