TABLE 1.

Selective pressure sites in the HN and F protein of HPIV1–3 obtained in this study^a

Virus	Clade/lineage/ sub-lineage	Viral protein	SLAC		FUBAR		FEL		MEME
			PSS	NSS	PSS	NSS	PSS	NSS	PSS
HPIV1	B	HN	0	1	1	14	0	11	0
	C		0	0	0	0	0	1	0
	D		0	0	0	0	0	0	0
HPIV2	G3		0	0	0	7	0	8	0
	G1a		0	0	0	0	0	9	0
HPIV3	3a		0	4	0	23	0	15	0
	3b		0	1	0	9	0	7	0
	3f		0	8	0	28	0	21	0
HPIV1	B	F	0	2	0	17	0	10	0
	C		0	0	0	0	0	2	0
	D		0	0	0	0	0	1	0
HPIV2	G3		0	0	0	5	0	6	0
	G1a		0	0	1	1	0	5	0
HPIV3	3a		0	6	0	32	0	25	1
	3b		0	0	0	8	0	4	0
	3f		0	10	0	39	0	35	0

^a The selective pressure sites of HN and F protein of HPIV1–3 sequenced in this study were calculated by clade/lineage/sub-lineage. A P-value of less than 0.05 for SLAC, FEL, and MEME, while Bayes factor/posterior probability of greater than 0.95 for FUBAR (7, 27).