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. 2024 Sep 24;221(10):e20240637. doi: 10.1084/jem.20240637

Table 1.

Estimation of the risk of severe TBE in auto-Ab-positive individuals relative to the general population

Anti-type I IFN auto-Ab (amount of type I IFN neutralized, in plasma diluted 1:10) OR (95% CI) P value
Anti-IFN-α2 (10 ng/ml) 8.1 (1.8–37.4) 0.0005565
Anti-IFN-ω (10 ng/ml) 12.3 (3.0–51.4) 0.0000022
Anti-IFN-α2 (10 ng/ml) and/or anti-IFN-ω (10 ng/ml) and/or anti-IFN-β (10 ng/ml) 8.7 (2.3–33.7) 0.0000053
Anti-IFN-α2 (10 ng/ml) and anti-IFN-ω (10 ng/ml) 20.8 (4.5–97.4) 0.0000009
Anti-IFN-α2 (100 pg/ml) 2.9 (0.6–13.5) 0.0726972
Anti-IFN-ω (100 pg/ml) 7.2 (2.1–24.4) 0.0000002
Anti-IFN-α2 (100 pg/ml) and/or anti-IFN-ω (100 pg/ml) and/or anti-IFN-β (10 ng/ml) 4.9 (1.5–15.9) 0.0000113
Anti-IFN-α2 (100 pg/ml) and anti-IFN-ω (100 pg/ml) 7.4 (1.6–34.3) 0.0011799