Table 2. G6PDH cryo-EM structures.

PDB code; name; organism; reference	Resolution (Å)	Primary citation of related structures as listed in the PDB entry (these include entries with symmetry applied as well as no symmetry applied)	PDB validation assessment (clashscore; Ramachandran outliers; side-chain outliers; specific comments of interest based on the PDB report)
7sng; G6PD WT tetramer; H. sapiens; Wei et al. (2022 ▸)	2.8	7snf, 7snh, 7sni, 7toe, 7tof, 7ual, 7uc2	10; 0.2%; 0.4%; portions not modelled were the N-terminal 1–28, 424–432 and 505–523 in chains A, B, C and D
7snh; G6PD D200N tetramer bound to NADP+; H. sapiens; Wei et al. (2022 ▸)	2.2	7snf, 7sng, 7sni, 7toe, 7tof, 7ual, 7uc2	6; 0%; 3.2%; portions not modelled were the N-terminal 1–27, 425–432 and 512–523 in chains A, B, C and D
7sni; G6PD D200N tetramer bound to NADP+ and G6P; H. sapiens; Wei et al. (2022 ▸)	2.5	7snf, 7sng, 7snh, 7toe, 7tof, 7ual, 7uc2	8; 0; 0.8%; 7%; portions not modelled were the N-terminal 1–27 and 516–523 in chains A, B, C and D
7snf; G6PD WT dimer; H. sapiens; Wei et al. (2022 ▸)	3.5	7sng, 7snh, 7sni, 7toe, 7tof, 7ual, 7uc2	16; 0.1%; 0%; portions not modelled were the N-terminal 1–26, 425–432 and 505–523 in chains A and B
8em2; H6PD (GDH/6PGL endoplasmic bifunctional protein); H. sapiens; Su et al. (2022 ▸)	3.02	7uzm, 8ekw, 8eky, 8emr, 8ems, 8emt, 8ene, 8eoj, 8eor	6; 0%; 3.4%; 37% of both chains A and B not modelled