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. 2024 Sep 18;80(Pt 10):269–277. doi: 10.1107/S2053230X24008604

Figure 2.

Figure 2

Myr-CoA and inhibitor (IMP-0001173) binding by PvNMT. The interactions were analyzed with Discovery Studio Visualizer (https://discover.3ds.com/discovery-studio-visualizer). (a) Stick representation of amino-acid residues (gray) interacting with Myr-CoA (green). (b) The Myr-CoA-binding pocket is slightly positively charged [shown in the same view as in (a)]. (c) The inhibitor IMP-0001173 (shown in cyan) interacts with amino acids (gray). (d) IMP-0001173 has primarily electrostatic interactions in the peptide-binding pocket.