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. 2024 Jun 25;147(10):3286–3305. doi: 10.1093/brain/awae204

Figure 2.

Figure 2

Cell types for cell therapy after stroke. Cell transplants can be derived either from the embryonic/fetal stages or the adult human. Adult stem cells comprise mesenchymal stem cells (MSCs) or differentiated cells from the peripheral blood reprogrammed to generate induced pluripotent stem cells (iPSCs). Both embryonic stem cells (ESC) and iPSCs can be differentiated into neural or glial-enriched stem cells to generate neurons, oligodendrocytes or astrocytes. Pericyte-like cells can be generated from iPSCs through neural crest cell intermediates.