TABLE. Characteristics of patients with Burkholderia multivorans ― four hospitals, California and Colorado, 2020–2024.
| Characteristic | No. (%) |
||||
|---|---|---|---|---|---|
| California |
Colorado |
Total N = 46 |
|||
| Hospital A* n = 13 |
Hospital B† n = 22 |
Hospital C§ n = 3 |
Hospital D¶ n = 8 |
||
|
Age, yrs, median (range)
|
60 (42–84) |
61 (21–93) |
61 (55–97) |
56 (34–68) |
60 (21–97)
|
|
Sex
| |||||
| Female |
4 (31) |
10 (45) |
0 (—) |
4 (50) |
18 (39)
|
| Male |
9 (69) |
12 (55) |
3 (100) |
4 (50) |
28 (61)
|
|
Source of index culture**
| |||||
| Respiratory |
11 (85) |
17 (77) |
2 (67) |
2 (25) |
32 (70)
|
| Blood |
2 (15) |
3 (14) |
1 (33) |
2 (25) |
8 (17)
|
| Intra-abdominal†† |
0 (—) |
0 (—) |
0 (—) |
4 (50) |
4 (9)
|
| Urine |
0 (—) |
2 (9) |
0 (—) |
0 (—) |
2 (4)
|
|
Admission characteristics of index hospitalization§§
| |||||
| Days from admission to index culture, median (range) |
15 (8–22) |
14 (0–117) |
30 (0–57) |
8 (2–17) |
14 (0–117)
|
|
Patient location at time of specimen collection
| |||||
| Medical intensive care unit |
13 (100) |
15 (68) |
2 (67) |
5 (62) |
35 (76)
|
| Medical-surgical ward |
0 (—) |
7 (32) |
1 (33) |
0 (—) |
8 (17)
|
| Other¶¶ |
0 (—) |
0 (—) |
0 (—) |
3 (38) |
3 (7)
|
| Deceased*** | 8 (62) | 9 (41) | 0 (—) | 4 (50) | 21 (46) |
* Hospital A was in northern California, and cases were identified during September 2020–October 2021.
† Hospital B was in southern California, and cases were identified during August 2021–February 2023.
§ Hospital C was in southern California, and cases were identified during January–April 2022.
¶ Hospital D cases were identified during April 2023–February 2024.
** Index culture is the first culture in which Burkholderia multivorans was isolated. If B. multivorans was isolated from blood and nonblood clinical specimens on the same day, the blood isolate was considered as the index culture.
†† Includes biliary fluid (two), peritoneal fluid (one), and perihepatic abscess fluid (one).
§§ Index hospitalization is the hospitalization that occurs when the index culture is identified and includes the period from admission to discharge. Transmission of B. multivorans before the index hospitalization cannot be ruled out for patients with frequent hospital admissions.
¶¶ Includes solid organ transplant unit (two) and medical telemetry unit (one).
*** Based on information from medical records; timing and cause of death was not ascertained.