Table 1. DSF and DLS of SOSIP.v9 proteins and SOSIP-I53-50 NPs.

	Thermostability (DSF)	Morphology (DLS)
	Tm (°C)	Rh (Å)	Pd (%)	Mass (%)
AMC009 SOSIP.v5.2	70.0	n.d.	n.d.	n.d.
AMC011 SOSIP.v5.2	68.5	n.d.	n.d.	n.d.
AMC008 SOSIP.v9	76.6	72	10.5	100
AMC009 SOSIP.v9	79.1	73	12.4	100
AMC011 SOSIP.v9	78.9	73	22.9	100
AMC016 SOSIP.v9	81.5	73	16.6	98.3
TRO.11 SOSIP.v9	76.5	74	17.4	100
AMC008 SOSIP-I53-50 NP	n.d.	264	17.8	100
AMC009 SOSIP-I53-50 NP	n.d.	261	15.6	100
AMC011 SOSIP-I53-50 NP	n.d.	253	14.7	99.3
AMC016 SOSIP-I53-50 NP	n.d.	246	16	93.4
TRO.11 SOSIP-I53-50 NP	n.d.	252	15	100
Mosaic SOSIP-I53-50 NP	n.d.	292	27.2	99.0