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. Author manuscript; available in PMC: 2024 Oct 3.
Published in final edited form as: Metabolomics. 2023 Apr 6;19(4):37. doi: 10.1007/s11306-023-02004-y

Table 1.

Demographic and clinical characteristics between control group, PMR and EORAneg at baseline

Variable Control
N=18
PMR
N=20
EORAneg
N=28
p
Female, n (%) 11(61) 17(85) 12(43) *** 0.01
Age, years 75.39±6.04 76.40±4.99 76.75±6.99 0.76
BMI, kg/m2 28.84±5.56 27.27±4.32 28.82±4.76 0.50
DM, n (%) 3(16) * 5(25) 15(54) *** 0.02
HBP, n (%) 11(61) 17(85) 20(71) 0.25
DL, n (%) 9(50) 12(60) 19(67) 0.48
CRP mg/dL 4.10±6.78* 31.56±28.27 41.57±52.14 0.02
ESR mm/h 17.93±17.03* 57.80±21.50** 52.54±27.20 <0.001
TNF (pg/mL) 15.05±19.86 13.60±6.12 13.86±6.68 0.93
IL-6 (pg/mL) 1.04±1.43* 11.25±23.92 19.93±29.45 0.03
Fatigue, n (%) 14 (70) 20 (71.4) 0.92
Weight loss, n (%) 8 (40) 10 (36) 0.76
Anorexia, n (%) 7 (35) 14 (50) 0.30
Stiffness, n (%) 19 (95) 27 (96) 0.81
Shoulder pain, n (%) 20 (100) 21 (75) 0.02
Pelvis pain, n (%) 18 (90) 13 (64) <0.001
Tender Joints 2.70 ± 0.98 9.11 ± 5.83 <0.001
Swollen Joints 0.25 ± 0.64 11.46 ± 5.89 <0.001
Pain 81.25 ± 17.46 73.04 ± 17.81 0.12
HAQ 1.50 ± 0.57 1.77 ± 0.80 0.18
DAS-CRP 5.64±0.99
DAS-ESR 6.21±1.00
NSAIDs mg 520.00 ± 44.72 450.00 ± 216.35 0.35
NSAIDs, n (%) 5 (25) 11 (39.3) 0.36

Continuous variables expressed in mean ± standard deviation; Categorical variables expressed as percentages. Quantitative variables between three groups were analyzed using ANOVA (Scheffe post-hoc). Student t-test was used to compare quantitative variables between variables present only in EORAneg and PMR. Chi-square analysis was used to determine the significance between groups for qualitative variables. Note. BMI: Body mass index; DM: Diabetes mellitus; HBP: high blood pressure; DL: Dyslipidemia; ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein; TNF: Tumor necrosis factor; IL-6: Interleukin 6.

*

p<0.05 Control vs EORAneg

**

p<0.05 Control vs PMR

***

p<0.05 EORAneg vs PMR