Chart 1. Differences in definition and management between chronic lung disease of prematurity and bronchopulmonary dysplasia.

Disease	Definition	Management
CLDP	This comprises a spectrum of respiratory pathologies resulting from prematurity, ranging from minimal respiratory symptoms with some loss of lung function to more severe cases. Viral bronchiolitis caused by RSV or other viral infections, recurrent wheezing, and asthma in school-age children are major causes of morbidity associated with CLDP.	• RSV prevention
		• Inhaled steroids for patients with atopy and symptoms of asthma
		• The use of immunostimulants like bacterial lysate as an option to prevent recurrent respiratory infections
BDP	This is the most severe clinical complication within the CLDP spectrum, defined as the need for supplemental oxygen or ventilation for 28 days or more from birth to 36 weeks post-conception.	• Follow-up with pulmonary function tests
		• RSV monoclonal antibodies
		• Asthma treatments only for specific groups
		• If supplemental oxygen use is recommended, a target saturation of >90%

CLDP: chronic lung disease of prematurity; RSV: respiratory syncytial virus; and BDP: bronchopulmonary dysplasia.