TABLE 2.
Recovery of virus from mouse brains infected with wild-type WSN or mutant WSN virusa
| Virus | Amt of virus inoculated into brain (log10 PFU) | Virus titer (mean log10 PFU/g ± SD) |
|---|---|---|
| Wild-type WSN | 4.6 | 5.30 ± 0.32 |
| 5.6 | 4.76 ± 0.43b | |
| 6.6 | 4.83 ± 0.26 | |
| WSN-453R | 4.6 | NRc |
| 5.6 | NR | |
| 6.6 | NR | |
| WSN-453L | 4.6 | NR |
| 5.6 | NR | |
| 6.6 | NR |
a
Five BALB/c mice were inoculated intracerebrally for each dilution of virus. Three days after infection, viruses in brains were titrated in MDCK cells.
b
Virus was recovered from three of the five mice infected.
c
NR, virus was not recovered (<5.0 × 101 PFU/g).