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. 2024 Sep 20;15:1354926. doi: 10.3389/fimmu.2024.1354926

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Copyright © 2024 Wu, Wang, Wu, Tao, Li, Zheng, Xu, Du, Zhao, Liang, Xu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ScRNA-seq transcriptome analysis of cell clusters in SAP patients and healthy controls. (A) The study’s workflow diagram. (B) Uniform manifold approximation and projection (UMAP) embedding of integrated single-cell transcriptomes of SAP and healthy control samples. Cells are colored by subtype. (C) Visualization of SAP dataset vs. healthy control dataset using UMAP embedded graphs. (D) Comparison of the percentages of monocyte clusters between SAP patients and controls. (E) Dot plots of canonical markers (columns) for major cell types (rows). Control, healthy controls; SAP, severe acute pancreatitis.