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. 2024 Sep 20;15:1444010. doi: 10.3389/fimmu.2024.1444010

Table 1.

Summary of clinical time-course.

CAR-T day +7 +8 to +10 +19 +27 +28 +29 +30 to +60 +61 to +82 +83 to +91 +92 to +107 +108
ALC 40 20–43 2,030 1,030 1,400 920 40–500 100–170
Events Gr. II CRS;
Gr. II ICANS
Re-admit Pneumonia
Resp. failure
Regained enteral access (PEG) Hemoptysis, Sepsis, Death
MNT status
Immunotherapies Toci. IVIg
Steroids Dex. Dex. Dex. Dex. Dex. Dex. Dex. Dex.
Dopaminergic therapies Carbidopa/levodopa (C/L) C/L C/L C/L
Ropinirole
Amantadine
C/L
Ropinirole
Amantadine
C/L
Ropinirole
Amantadine

ALC , Absolute Lymphocyte Count; Dex., Dexamethasone; PEG , Percutaneous Endoscopic Gastrostomy; Toci. , Tocilizumab. Shading represents MNT symptoms, where darker shading represents more severe symptoms.