Table 3.
4C pivotal | 4C HCUV | SEIMC pivotal | SEIMC HCUV | |
---|---|---|---|---|
Youden cut-off, point | 13 (11–13) | 9.5 (7.5–10.5) | 8.5 (7.5–9.5) | 7.5 (6.5–7.5) |
Specificity | 0.75 (0.56–0.76) | 0.83 (0.75–0.89) | 0.66 (0.62–0.71) | 0.79 (0.73–0.83) |
Sensitivity | 0.64 (0.62–0.82) | 0.95 (0.87-1) | 0.84 (0.79–0.87) | 0.97 (0.9-1) |
Positive predictive value | 0.28 (0.27–0.36) | 0.06 (0.06–0.07) | 0.24 (0.23–0.25) | 0.07 (0.06–0.07) |
Negative predictive value | 0.98 (0.98–0.99) | 0.88 (0.88–0.89) | 0.97 (0.97–0.98) | 0.89 (0.88–0.90) |
Positive likelihood ratio | 2.52 (1.40–3.43) | 5.63 (3.43–9.03) | 2.45 (2.05-3) | 4.73 (3.36–6.05) |
Negative likelihood ratio | 0.48 (0.23–0.68) | 0.06 (0-0.17) | 0.24 (0.18–0.35) | 0.03 (0-0.14) |
Bracketed number indicate 95% confidence interval.
HCUV, Hospital Clínico Universitario de Valladolid.