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. 2024 Jul 3;71(4):464–480. doi: 10.1165/rcmb.2023-0402OC

Figure 2.

Figure 2.

Plasma EVs from infants on HO2 contain higher percentages of alveolar macrophage–derived ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain). (A–F) Flow cytometry analysis of LO2-EVs (A) and HO2-EVs (B) demonstrated that HO2-EVs had higher percentages of ASC+ (C), CD11b+/ASC+ (D), CD11c+/ASC+ (E), and CD206+/ASC+ (F) EVs compared with LO2-EVs. (G–I) Flow cytometry of nondepleted EVs (G) and depleted EVs (H) showed that the depletion protocol effectively removed the majority of CD11b+/ASC+ EVs (I). n = 5–7 per group. *P < 0.05, **P < 0.01, and ***P < 0.001.