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Ribbon representation showing a front view of the N-terminal core domain of HIV-1 CA. The β-hairpin structure, CypA binding loop, and seven α-helices are labeled (20, 38). Note that the helices are numbered as described by Gitti et al. (20). The three residues mutated in this study, W23, F40, and D51, are located in helices I, II, and III, respectively. The diagram was generated with Molscript (32).
