. Author manuscript; available in PMC: 2024 Oct 4.

Published in final edited form as: Leukemia. 2020 Jun 16;34(11):2914–2924. doi: 10.1038/s41375-020-0916-8

Table 2:

Responses

CPX-351	All	50 units/m²	75 units/m²	100 units/m²	P

CR	16 (29)	3 (19)	6 (25)	7 (44)
CRi	3 (5)	0	3 (13)	0
CR+CRi	19 (34)	3 (19)	9 (38)	7 (44)	0.35^*
Treatment failure	37 (66)	13 (81)	15 (62)	9 (56)
No response	36 (64)	13 (81)	14 (58)	9 (56)
Death in aplasia	0	0	0	0
Death from indeterminate cause	1 (2)	0	1 (4)	0
MRD negative	4 (21)^{^}	0	1 (4)	3 (19)	0.16

Values are n (%). Abbreviations: CR, complete response; CRi, CR with incomplete hematologic recovery; MRD, minimal residual disease: assessed following induction.

Comparison of CR+CRi among 3 cohorts.

^{^}

Four (21%) of the 19 patients that achieved CR/CRi had undetectable MRD following induction.