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. Author manuscript; available in PMC: 2024 Oct 4.
Published in final edited form as: Ann Intern Med. 2024 Mar 5;177(3):303–314. doi: 10.7326/M23-1990

Table 3. Marginal Adjusted Cumulative Mortality Riska by Hispanic/Latino Background based on the Progressively Adjusted Modelsb.

Summary Central American Cuban Dominican Mexican Puerto Rican South American
 Person-Yearsa 18671.31 24412.68 15015.66 70854.84 27626.74 11495.78
 Deathsa 86 211 75 288 246 40
Before the Pandemic: 11-Year Cumulative Mortality Risk
Model 1 (Age and Sex)
 Mortality Risk 4.0% 5.7% 3.7% 3.7% 6.3% 2.4%
 95% CI (3.1%, 5.1%) (5.0%, 6.6%) (2.6%, 5.3%) (3.0%, 4.5%) (5.2%, 7.6%) (1.7%, 3.5%)
Model 2 (Age, Sex, and SES)
 Mortality Risk 4.0% 5.7% 3.4% 3.8% 6.0% 2.6%
 95% CI (3.1%, 5.2%) (4.9%, 6.7%) (2.4%, 4.9%) (3.1%, 4.7%) (4.9%, 7.3%) (1.8%, 3.8%)
Model 3 (Age, Sex, SES, and Acculturation-Related Factors)
 Mortality Risk 4.3% 6.1% 3.7% 3.8% 5.3% 2.8%
 95% CI (3.4%, 5.6%) (5.2%, 7.1%) (2.6%, 5.2%) (3.1%, 4.7%) (4.3%, 6.5%) (1.9%, 4.1%)
Model 4 (Age, Sex, SES, Acculturation-Related, and Lifestyle Factors)
 Mortality Risk 4.6% 5.0% 4.4% 5.4% 4.3% 2.8%
 95% CI (3.6%, 6.0%) (4.2%, 5.8%) (3.1%, 6.4%) (4.2%, 6.9%) (3.3%, 5.5%) (1.9%, 4.1%)
Model 5 (Age, Sex, SES, Acculturation-Related, Lifestyle, and Clinical Factors)
 Mortality Risk 4.9% 4.6% 4.3% 5.6% 4.3% 3.4%
 95% CI (3.8%, 6.3%) (3.9%, 5.4%) (3.0%, 6.2%) (4.4%, 7.1%) (3.4%, 5.5%) (2.4%, 5.0%)
During the Pandemic: 2-Year Cumulative Mortality Risk
Model 1 (Age and Sex)
 Mortality Risk 2.0% 1.4% 1.7% 1.5% 1.5% 1.1%
 95% CI (1.4%, 3.0%) (1.1%, 1.7%) (1.1%, 2.6%) (1.2%, 1.9%) (1.1%, 2.0%) (0.6%, 2.0%)
Model 2 Age, Sex, and SES)
 Mortality Risk 2.0% 1.4% 1.6% 1.6% 1.4% 1.2%
 95% CI (1.4%, 3.0%) (1.1%, 1.8%) (1.0%, 2.4%) (1.2%, 2.0%) (1.0%, 1.9%) (0.7%, 2.1%)
Model 3 (Age-Sex, SES, and Acculturation-Related Factors)
 Mortality Risk 2.1% 1.5% 1.7% 1.6% 1.2% 1.3%
 95% CI (1.5%, 3.1%) (1.2%, 1.8%) (1.1%, 2.5%) (1.2%, 2.0%) (0.9%, 1.7%) (0.7%, 2.2%)
Model 4 (Age, Sex, SES, Acculturation-Related, and Lifestyle Factors)
 Mortality Risk 2.1% 1.2% 1.9% 2.0% 1.0% 1.2%
 95% CI (1.5%, 3.1%) (1.0%, 1.5%) (1.3%, 2.7%) (1.6%, 2.6%) (0.7%, 1.5%) (0.7%, 2.1%)
Model 5 (Age, Sex, SES, Acculturation-Related, Lifestyle, and Clinical Factors)
 Mortality Risk 2.1% 1.1% 1.8% 2.0% 1.0% 1.4%
 95% CI (1.5%, 3.0%) (0.9%, 1.4%) (1.3%, 2.6%) (1.6%, 2.5%) (0.7%, 1.5%) (0.9%, 2.4%)

Abbreviations: CI: confidence intervals; SES: socioeconomic status

a

All values are weighted for study design and non-response except for person-years and number of deaths for which unweighted numbers are presented.

b

Model 1 estimated the difference in mortality risk among Hispanic/Latino groups after adjusting for age and sex. Progressive models were fit to investigate whether the disparity in mortality risk across Hispanic/Latino groups persist after accounting for socioeconomic, acculturation, lifestyle, and clinical related factors. Model 2 added socioeconomic status (income, education, and health insurance). Model 3 added acculturation related factors (place of birth /age at immigration, language preference). Model 4 was additionally adjusted for lifestyle characteristics (diet, physical activity), and Model 5 added clinical factors (major CVD risk factors, family history of CHD, stroke, or cancer, prevalent chronic comorbidities, and elevated depressive symptoms).