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. Author manuscript; available in PMC: 2024 Oct 4.
Published in final edited form as: Annu Rev Genomics Hum Genet. 2024 Aug 6;25(1):77–104. doi: 10.1146/annurev-genom-021623-081639

Figure 3.

Figure 3

Illustrating the HPRC pangenome with an example. (a) The structural haplotypes of the CYP2D6 and CYP2D7 genes called from the Minigraph-Cactus HPRC pangenome graph. The color gradients are based on the relative positions of the genes: Green represents the head of a gene, and blue represents the end of a gene. (b) Different paths taken by different structural haplotypes in the graph. The color gradient is based on path position: Red represents the head of a path, and blue represents the end of a path. (c) Frequency and linear structural visualization of all structural haplotypes called by the Minigraph-Cactus graph. Abbreviation: HPRC, Human Pangenome Reference Consortium. Figure adapted from Reference 93 (CC BY 4.0) with assistance from Shuangjia Lu.