Table 3.
Multidimensional Classifier Test Performance Characteristics for Predicting 18-Month Death or Transplant When Applied to Independent IPF and Non-IPF ILD Validation Cohorts
| Classification | IPF validation cohort (n = 105) | Non-IPF ILD validation cohort (n = 295) | ||
|---|---|---|---|---|
| Outcome (+) | Outcome (−) | Outcome (+) | Outcome (−) | |
| High risk | 21 | 6 | 38 | 47 |
| Low risk | 9 | 69 | 16 | 194 |
| Sensitivity | 0.70 | 0.70 | ||
| Specificity | 0.92 | 0.80 | ||
| (+) Predictive value | 0.78 | 0.45 | ||
| (−) Predictive value | 0.88 | 0.92 | ||
| (+) Likelihood ratio | 8.75 | 3.61 | ||
| (−) Likelihood ratio | 0.33 | 0.37 | ||
Abbreviations: ILD, interstitial lung disease; IPF, idiopathic pulmonary fibrosis.