TABLE 1.

Gag and Gag-Pol cleavage sites for HIV-1 and FIV

Virus	Gag and Gag-Pol cleavage sites
	P4a	P3	P2	P1	P1′b	P2′	P3′	P4′
FIV
MA/CA	P	Q	A	Y	P	I	Q	T
CA/NC1	K	M	Q	L	L	A	E	A
CA/NC2	T	K	V	Q	V	V	Q	S
NC (internal)	V	N	Q	M	Q	Q	A	V
NC/PR	G	F	V	N	Y	N	K	V
PR/RT	R	L	V	M	A	Q	I	S
RT/RNase H	A	E	T	W	Y	I	D	G
RNase H/DU	C	Q	T	M	M	I	I	E
DU/IN	T	G	V	F	S	S	W	V
HIV-1
MA/CA	S	Q	N	Y	P	I	V	Q
CA/P2	A	R	V	L	A	E	A	M
P2/NC	A	T	I	M	M	Q	R	G
P1/P6	P	Q	N	F	L	Q	S	R
in P6	K	E	L	Y	P	L	T	S
TF/PR	S	F	N	F	P	Q	I	T
PR/RT	T	L	N	F	P	Q	I	T
in RT	A	E	T	F	Y	V	D	G
RT/IN	R	K	I	L	F	L	D	G

^aBerger and Schechter nomenclature. 

^bHydrolysis occurs between the P1 and P1′ amino acids.