Skip to main content
. 2001 Oct;75(19):9458–9469. doi: 10.1128/JVI.75.19.9458-9469.2001

TABLE 5.

Kinetics of cleavage of Ac-KSGVFVVNGK-NH2 with HIV-1 PR and FIV PRa

PR type Mean Km (μM) ± SD Mean kcat (s−1) ± SD Mean kcat/Km (μM−1 s−1) (10−4) ± SD
FIV 2,100 ± 300 0.70 ± 0.08 3.4 ± 0.8
HIV-1 420 ± 40 0.35 ± 0.02 8 ± 1
a

Peptide cleavage kinetics of HIV-1 PR and FIV PR cleavage of Ac-KSGVF↓VVNGK-NH2 at pH 6.7 in 0.2 M NaCl and 0.1 M MES are shown. Errors are shown as 1 standard deviation of the data from three trials.