Table 3:

Functional classification of the differentially expressed transcripts between the midguts of the G4 and G3 A. americanum adult females.

Class	No. of transcripts		G3 TPM	G4 TPM	G4/G3 TPM
	Down	Up
Immunity	10	11	4944.51	35993.81	7.28
Oxidant metabolism	18	23	5841.90	35485.70	6.07
Peptidase Inhibitor	2	14	1005.71	4655.89	4.63
Nuclear export	0	2	17.07	66.44	3.89
Protein export	15	14	1133.67	4007.39	3.53
Cytoskeletal	10	14	2394.23	7356.28	3.07
Transposable element	22	13	505.5167	1340.037	2.65
Met/Lipd	24	12	4444.32	11667.91	2.63
Extracellular matrix	12	4	632.44	1649.09	2.61
Secreted	209	136	16503.82	40711.89	2.47
Protease	7	4	188.53	457.10	2.42
Protein modification	7	4	459.26	1104.46	2.40
Met/AA	7	13	225.45	540.82	2.40
Met/Energy	13	7	1023.75	1929.56	1.88
Unknown	715	356	24839.76	44302.71	1.78
Met/Int	4	3	150.58	213.98	1.42
Met/Carb	9	7	314.91	440.33	1.40
Signal transduction	61	12	735.47	585.38	0.80
Transporters	52	15	1025.65	807.87	0.79
Transcription machinery	36	5	369.54	270.60	0.73
Nuclear regulation	6	2	34.77	17.14	0.49
Proteasome	5	3	53.58	22.56	0.42
Met/Nuc	4	1	116.74	17.06	0.15
Protein synthesis	5	0	40.94	4.97	0.12
Transcription factor	3	0	37.82	4.03	0.11
Storage	3	0	32.86	1.84	0.06

^*TPM: Transcript Per Million