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[Preprint]. 2024 Aug 10:2024.08.10.607452. [Version 1] doi: 10.1101/2024.08.10.607452

Table 4:

Effect allele, effect size and p-values reported by the 4 GWAS studies of AD for the 3 SNPs identified as eQTLs associated with TAS2R41 and TAS2R60. Two of the SNPs are not reported by Marioni et al.

GWAS Study GWAS stats/info rsll762262 rs11771145 rs10228407

Wightman et al. PMID 34493870 log Odds −0.07 −0.05 0.06
P-Value 9.80e-08 3.81e-07 2.71e-08
Mapped Gene (location) EPHA1-AS1 (intron) EPHA1-AS1 (intron) EPHA1-AS1 (intron)
Effect allele reported T A T

Marioni et al. PMID 29777097 log Odds Not reported Not reported 0.05
P-Value Not reported Not reported 1.28e-09
Mapped Gene (location) Not reported Not reported EPHA1-AS1 (intron)
Effect allele reported Not reported Not reported T

Bellenguez et al. PMID 35379992 Odds-Ratio 0.94 0.94 1.05
P-Value 6.35e-10 1.29e-12 1.24e-10
Mapped Gene (location) EPHA1-AS1 (intron) EPHA1-AS1 (intron) EPHA1-AS1 (intron)
Effect allele reported T A T

Jansen et al. PMID 30617256 log Odds −0.016 −0.011 −0.01
P-Value 5.22e-09 8.84e-07 9.33e-06
Mapped Gene (location) EPHA1-AS1 (intron) EPHA1-AS1 (intron) EPHA1-AS1 (intron)
Effect allele reported T A G