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[Preprint]. 2024 Sep 18:2024.09.16.24313761. [Version 1] doi: 10.1101/2024.09.16.24313761

Table 3.

Comparison of Psychological and Clinical Characteristics for Persistent Post-Traumatic Headache Subgroups Identified from Biologic Features

Low Coping
(N=20)
High Coping
(N=13)
P-Value
Psychological Characteristics
PROMIS Depression (T-score) 56.9 (7.3) 54.2 (9.1) 0.364
PROMIS Anxiety (T-score) 61.3 (5.7) 58.2 (5.4) 0.125
Combat Exposure Scale (0–41 points)* 18.0 (21.8) 12.0 (18.5) 0.650
PTSD Checklist for DSM-5 (0–80 points) 39.6 (16.4) 30.0 (10.7) 0.073
Pain Anxiety Symptoms Scale (0–100 points)* 40.5 (32.3) 14.0 (29.0) 0.009
Pain Catastrophizing Scale (0–52 points)* 18.0 (12.0) 8.0 (12.0) 0.004
Pain Self-Efficacy Questionnaire (0–60 points) 32.2 (9.4) 44.1 (15.6) 0.010

Clinical Characteristics
Headache Impact Test-6 (36–78 points) 63.2 (4.4) 56.1 (8.4) 0.012
Headache Type
 Migraine-like 4 (20) 1 (7) 0.327
 TTH-like 0 (0) 1 (7)
 Mixed 16 (80) 11 (86)
PROMIS Pain Intensity – Headache (T-score) 59.9 (6.8) 56.6 (7.3) 0.186
Headache frequency
 Once a month or less 0 (0) 2 (15) 0.428
 Once a week 6 (30) 3 (23)
 Several times a week 11 (55) 6 (47)
 Daily or Constant 3 (15) 2 (15)
PROMIS Pain Intensity – Neck Pain (T-score) 59.3 (10.3) 58.6 (5.7) 0.837
Neck pain frequency
 Once a month or less 4 (20) 1 (8) 0.320
 Once a week 5 (25) 1 (8)
 Several times a week 2 (10) 4 (31)
 Daily or Constant 9 (45) 7 (53)

Values are number (%) or mean (SD) unless otherwise noted as *median (IQR)

PROMIS=Patient-Reported Outcome Measurement Information System; PTSD=Post-traumatic stress disorder; DSM = Diagnostic and Statistical Manual of Mental Disorders, TTH=Tension Type Headache