Table 4.

Univariate and multivariate logistic regression analysis of risk factors associated with DI in postoperative period

Variables	Univariate regression analysis		Multivariate regression analysis
	OR (95% CI)	P	OR (95% CI)	P
Age	0.63 (0.4-0.97)	<0.05	0.61 (0.36-1.03)	0.07
Sex	1.0 (0.3-3.1)	0.97	0.84 (0.2-3.3)	0.80
Knosp grading	4.1 (1.2-13.9)	<0.05	4.0 (0.95-17.2)	0.06
Wilson–Hardy grading (sellar floor involvement)	3.5 (0.96-13.0)	0.06
Wilson–Hardy grading (suprasellar/parasellar involvement)	3.6 (0.8-15.7)	0.09
Apoplexy	5.2 (1.2-22.3)	<0.05	6.4 (1.1-36.4)	<0.05
Adenoma volume	1.3 (0.98-1.6)	0.07
Duration of surgery	2.3 (1.7-4.9)	<0.05	2.6 (1.04-6.5)	<0.05
Intraoperative pituitary visible	0.6 (0.2-1.9)	0.4
Intraoperative CSF leak	1.3 (0.3-5.0)	0.74

DI: Diabetes insipidus, OR: odd ratio, CI: confidence interval, CSF: cerebral spinal fluid. Duration of surgery. For purpose of analysis, age was in units of 10 years, adenoma in the unit of 5 mm