Table 4.

Factors influencing clinical remission in patients with subgroups analysis

Subgroup	Multivariate
Variables	Beta (95% CI)	P
Gender
Male
Vit-D	− 2.942 (− 4.93 to − 0.954)	0.005
ESR	0.95 (0.1–1.799)	0.03
Hs-CRP	− 0.618 (− 1.178 to − 0.058)	0.032
Female
RBC	− 47.136 (− 81.29 to − 12.982)	0.011
Hs-CRP	0.886 (0.409–1.363)	0.002
MCV	− 1.612 (− 3.189 to − 0.034)	0.046
BMI
Normal
Hb	− 1.505 (− 2.66 to − 0.35)	0.014
Folic acid	− 7.674 (− 13.081 to − 2.266)	0.009
FBG	18.203 (4.236–32.17)	0.014
Smoking
Yes
ESR	1.102 (0.381–1.823)	0.009
K	− 62.436 (− 98.176 to − 26.697)	0.004
No
Vit-D	− 3.449 (− 5.406 to − 1.493)	0.001
BMI	− 4.214 (− 7.845 to − 0.582)	0.024
CRP	0.282 (0.03–0.533)	0.029
Intestinal surgery
No
Vit-D	− 2.284 (− 4.193 to − 0.376)	0.021
ESR	1.493 (0.609–2.378)	0.002
Hs-CRP	− 0.677 (− 1.23 to − 0.124)	0.018
Yes
RBC	− 38.407 (− 64.477 to − 12.338)	0.008
BUN	− 18.395 (− 31.307 to − 5.484)	0.009
Perianal surgery
No
Vit-D	− 2.991 (− 5.459 to − 0.523)	0.022
CRP	0.35 (0.013–0.688)	0.043
Course of disease	4.604 (0.4–8.809)	0.035
Yes
Vit-D	− 4.169 (− 7.922 to − 0.416)	0.033
TB	− 5.7 (− 9.162 to − 2.239)	0.005
Blood P	− 147.827 (− 248.852 to − 46.802)	0.009
ANA	− 82.995 (− 141.145 to − 24.845)	0.01
Combined IMM
No
Vit-D	− 2.194 (− 4.003 to − 0.385)	0.02
WBC	5.094 (1.019–9.169)	0.017
Yes
ESR	1.757 (0.742–2.771)	0.002
RBC	− 21.1 (− 41.65 to − 0.549)	0.045
Hb	1.172 (0.281–2.063)	0.014
DB	− 22.948 (− 44.891 to − 1.005)	0.042
BUN	− 17.693 (− 27.591 to − 7.796)	0.002

Vit-D, vitamin D; ESR, erythrocyte sedimentation rate; Hs-CRP, high-sensitivity C-reaction protein; RBC, red blood cell; MCV, mean corpuscular volume; BMI, body mass index; Hb, hemoglobin; FBG, fasting blood glucose; CRP,C-reactive protein; BUN, urea; TBil, total bilirubin; ANA, antinuclear antibodies; WBC, white blood cell; DBil, direct bilirubin