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. 2024 Oct 4;15:8606. doi: 10.1038/s41467-024-52573-2

Table 3.

Summary of in vitro JNK1 PhALC assay (with 10 mM GSH) results with compounds containing the same warhead with modified ATP-competitive fragments

graphic file with name 41467_2024_52573_Tabq_HTML.gif R2 PhALC IC50/(nM)
1aR-IN-7 graphic file with name 41467_2024_52573_Tabr_HTML.gif 17 ± 5
1aR-IN-9 graphic file with name 41467_2024_52573_Tabs_HTML.gif 12 ± 1
1aR-IN-10 graphic file with name 41467_2024_52573_Tabt_HTML.gif 13 ± 2
1aR-isoPHEN graphic file with name 41467_2024_52573_Tabu_HTML.gif 16 ± 2

(Data show the mean±parameter error estimate from weighted least squares method; n = 3, independent experiments).