Table 1. Summary of BRIGHT protocol.
Note on abbreviations: * The UK only; ▵ The Gambia only; ^ Recorded every two weeks from 2 weeks to 24 months of age; L,W, H, HC,MUAC, KHL (L – length, W – weight, H – height, HC – head circumference, MUAC – mid to upper arm circumference, KHL – knee to heel length).
| Study Measure Time point: | Antenatal | Birth | 7–14
d |
1
mo |
5
mo |
8
mo |
12
mo |
18
mo |
24
mo |
|---|---|---|---|---|---|---|---|---|---|
| Neuroimaging measures | |||||||||
| fNIRS: Social/Non-social | x | x | x | x | x | x | |||
| fNIRS: Habituation and Novelty Detection | x | x | x | x | x | x | |||
| fNIRS: Functional connectivity | x | x | x | x | x | x | |||
| fNIRS: Working memory | x | x | x | x | |||||
| fNIRS */Behavioural: Deferred imitation | x | x | |||||||
| EEG: Auditory Oddball | x | x | x | ||||||
| Behavioural/Neurocognitive measures | |||||||||
| Neonatal Behavioural Assessment Scale (NBAS) | x | ||||||||
| Eye-tracking: Cognitive control | x | x | x | x | x | ||||
| Eye-tracking: Habituation | x | x | x | ||||||
| Eye-tracking: Gap/Overlap | x | x | x | x | x | ||||
| Eye-tracking: Non-social contingency | x | x | x | ||||||
| Eye-tracking: Face popout | x | x | x | x | x | ||||
| Eye-tracking: Dynamic scenes | x | x | x | x | x | ||||
| Eye-tracking: Word-picture-matching | x | x | |||||||
| Mullen Scales of Early Learning (MSEL) | x | x | x | x | x | ||||
| Parent-Child Interaction | x | x | x | x | x | x | |||
| LENA language assessment in home | x | x | x | ||||||
| LENA in PCI | x ▵ | x ▵ | x ▵ | x ▵ | x | x | |||
| Tablet-based Cognitive Assessment * | x * | x * | |||||||
| Questionnaires/Interviews – Infant/Child | |||||||||
| Communication Development Inventory (CDI) | x | x | x | ||||||
| Adapted Oxford Sleep Diary | x | x | x | x | x | x | |||
| Food Frequency Q (FFQ) ▵ ^ | x | x | x | x | x | x | x | x | |
| Infant feeding online Q (IFQ) * ^ | x | x | |||||||
| Food diary (Intake24UK) * | x | x | x | x | |||||
| Early Childhood Development Index ^ | |||||||||
| Questionnaires/Interviews – Family | |||||||||
| Edinburgh Postnatal Depression Scale (EDPS)
– Maternal |
x | x | x | x | x | ||||
| Edinburgh Postnatal Depression Scale (EDPS)
– Paternal * |
x | x | x | x | x | ||||
| Pregnancy Related Anxiety form (PRAS)
– Maternal |
x | ||||||||
| Pregnancy Related Anxiety form (PRAS)
– Paternal * |
x | ||||||||
| Pregnancy Specific Anxiety (PSA) – Maternal | x | ||||||||
| Pregnancy Specific Anxiety (PSA) – Paternal * | x | ||||||||
| Positive Negative Affect Schedule (PANAS)
– Maternal |
x | x | x | x | |||||
| Positive Negative Affect Schedule (PANAS)
– Paternal * |
x | x | x | x | |||||
| Perceived Stress Scale (PSS) – Maternal | x | x | x | x | |||||
| Perceived Stress Scale (PSS) – Paternal * | x | x | x | x | |||||
| Socioeconomic Status (SES) | x * | x ▵ | x * | x | |||||
| Demographic and Family Information | x * | x ▵ | x * | x | x * | ||||
| Family details (from DSS – Gambia or antenatal
call UK) |
x | x * | x * | ||||||
| Family Caregiving Questionnaire (FCQ) | x | x | x | ||||||
| Family Care Indicators (FCI) ▵ | x | x | x | ||||||
| Clinical measures / Medical details | |||||||||
| Healthy Pregnancy Questionnaire * | x | ||||||||
| Antenatal Medical form * | x | ||||||||
| Delivery Information and Baby check ▵ | x | ||||||||
| Anthropometric measures – infant
(L,W,HC,MUAC, KHL) |
x
(L,W,HC) |
x
(L,W,HC) |
x | x | x | x | x | x | |
| Anthropometric measures – mother (W, H) | |||||||||
| Maternal blood sample ▵ | x | ||||||||
| Maternal urine sample ▵ | x | ||||||||
| Maternal breast milk sample ▵ | x | ||||||||
| Infant blood sample ▵ | x | x | x | x | x | x | |||
| Infant urine sample ▵ | x | x | x | ||||||