Table 1.
Description of general clinical parameters of the study population and the reference population.
| Characteristic* | LEAD study population | LEAD reference population | ||||
|---|---|---|---|---|---|---|
| Overall, N = 10,033 | Male, N = 4678 | Female, N = 5355 | Overall, N = 6828 | Male, N = 3036 | Female, N = 3792 | |
| Age (years) | 49.0 (16.4) | 49.0 (16.5) | 49.0 (16.3) | 43.1 (14.7) | 42.2 (14.4) | 43.9 (14.9) |
| Weight (kg) | 75.7 (16.2) | 84.5 (14.2) | 68.1 (13.8) | 72.8 (15.0) | 81.9 (13.0) | 65.6 (12.3) |
| Height (cm) | 170.4 (9.5) | 177.5 (7.0) | 164.2 (6.6) | 171.0 (9.4) | 178.5 (6.8) | 165.0 (6.4) |
| Systolic BP (mm Hg) | 131.6 (20.6) | 135.7 (19.6) | 128.0 (20.8) | 126.3 (18.0) | 131.0 (17.2) | 122.6 (17.7) |
| Diastolic BP (mm Hg) | 78.2 (11.3) | 80.5 (11.1) | 76.2 (11.1) | 76.4 (10.7) | 79.0 (10.5) | 74.3 (10.4) |
| Total cholesterol (mmol/L) | 5.4 (1.1) | 5.3 (1.1) | 5.5 (1.1) | 5.4 (1.1) | 5.3 (1.1) | 5.4 (1.1) |
| HDL cholesterol (mmol/L) | 1.7 (0.5) | 1.5 (0.4) | 1.9 (0.5) | 1.7 (0.5) | 1.5 (0.4) | 1.9 (0.5) |
| LDL cholesterol (mmol/L) | 3.2 (1.0) | 3.2 (1.0) | 3.2 (1.0) | 3.2 (1.0) | 3.3 (1.0) | 3.1 (1.0) |
| Triglycerides (mmol/L) | 1.3 (0.8) | 1.4 (1.0) | 1.1 (0.6) | 1.1 (0.7) | 1.3 (0.9) | 1.0 (0.5) |
| Glucose (mg/dl) | 94.1 (17.3) | 97.2 (19.3) | 91.4 (14.8) | 89.9 (8.8) | 92.0 (9.0) | 88.2 (8.3) |
| Smoking status | ||||||
| Never smoker | 4411 (44.0%) | 1783 (38.1%) | 2628 (49.1%) | 3138 (46.0%) | 1269 (41.8%) | 1869 (49.3%) |
| Ever smoker | 5619 (56.0%) | 2894 (61.9%) | 2725 (50.9%) | 3689 (54.0%) | 1766 (58.2%) | 1923 (50.7%) |
| Dyslipidaemia | 6966 (71.5%) | 3391 (74.2%) | 3575 (69.0%) | 4635 (68.2%) | 2166 (71.7%) | 2469 (65.4%) |
| Hypertension | 2037 (20.3%) | 1160 (24.8%) | 877 (16.4%) | 875 (12.8%) | 512 (16.9%) | 363 (9.6%) |
| Overt CVD | 1704 (17.0%) | 923 (19.7%) | 781 (14.6%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
| Treated diabetes mellitus | 475 (4.7%) | 293 (6.3%) | 182 (3.4%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
| Treated hypertension | 2295 (22.9%) | 1205 (25.8%) | 1090 (20.4%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
| Treated Dyslipidemia | 1072 (10.7%) | 583 (12.5%) | 489 (9.1%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
| Diabetes mellitus | 603 (6.2%) | 391 (8.5%) | 212 (4.1%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
*Data summarized as mean (Standard Deviation) for continuous and n (%) for categorical variables.