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. 2024 Oct 4;14:23063. doi: 10.1038/s41598-024-73400-0

Table 2.

Univariate analysis for the primary outcome and thromboembolic events.

Primary Outcome Thromboembolic event
HR (95% CI) P value HR (95% CI) P value
Age 1.02 (0.98–1.05) 0.326 0.99 (0.96–1.04) 0.935
Male sex 0.87 (0.42–1.80) 0.699 0.52 (0.21–1.30) 0.164
Body mass index 1.03 (0.91–1.15) 0.686 1.09 (0.94–1.25) 0.257
Hypertension 1.29 (0.61–2.74) 0.505 1.05 (0.44–2.48) 0.921
Diabetes mellitus 1.26 (0.48–3.30) 0.643 0.66 (0.15–2.82) 0.572
Chronic kidney disease 1.42 (0.43–4.70) 0.571 1.35 (0.31–5.86) 0.685
Previous stroke 1.65 (0.63–4.37) 0.311 0.83 (0.19–3.58) 0.798
Coronary artery disease 3.01 (1.37–6.57) 0.006 1.19 (0.39–3.67) 0.759
CHA 2 DS 2 -VASc score 1.28 (1.03–1.57) 0.023 1.09 (0.84–1.41) 0.507
Rheumatic heart disease 0.74 (0.28–1.93) 0.532 0.84 (0.28–2.49) 0.750
Bioprosthetic valve 0.99 (0.23–4.20) 0.988 1.56 (0.36–6.82) 0.554
Mechanical valve 0.92 (0.39–2.16) 0.850 1.14 (0.44–2.94) 0.792
Mitral valve repair 1.08 (0.49–2.37) 0.854 0.78 (0.32–1.88) 0.579
Aortic valve replacement 2.33 (0.99–5.45) 0.052 2.92 (1.13–7.54) 0.027
CABG 2.92 (1.00–8.53) 0.049 0.00 (0–Inf) 0.997
Tricuspid surgery 0.98 (0.45–2.13) 0.958 0.87 (0.36–2.14) 0.768
Maze 0.31 (0.13–0.77) 0.011 0.20 (0.06–0.69) 0.011
LV end-systolic diameter 1.03 (0.98–1.08) 0.208 1.02 (0.96–1.08) 0.585
LV end-diastolic diameter 1.02 (0.97–1.06) 0.519 1.01 (0.96–1.06) 0.705
LV ejection fraction 0.97 (0.94–1.00) 0.061 0.98 (0.94–1.02) 0.291
LA volume index 1.00 (0.99–1.01) 0.603 1.00 (0.99–1.01) 0.470
LAAO 0.22(0.08–0.63) 0.005 0.14 (0.03–0.62) 0.009
LAA shape, cauliflower 2.17 (1.00–4.67) 0.049 3.13 (1.30–7.52) 0.011
LA volume 1.00 (0.99–1.00) 0.752 1.00 (0.99–1.00) 0.378
LAA volume 1.01 (0.99–1.03) 0.327 1.01 (0.99–1.03) 0.139
LAA os diameter 1.00 (0.95–1.05) 0.970 1.02 (0.96–1.07) 0.577
LAA os perimeter 1.00 (0.99–1.02) 0.972 1.01 (0.99–1.02) 0.590
LAA os area 1.01 (0.94–1.10) 0.756 1.03 (0.94–1.13) 0.514
Adequate anticoagulation 0.78 (0.37–1.66) 0.520 1.16 (0.45–2.99) 0.761
Postoperative AF 1.97 (0.87–4.45) 0.103 2.41 (0.88–6.59) 0.086

CABG, coronary artery bypass grafting; LV, left ventricular; LA, left atrial; LAA, left atrial appendage; AF, atrial fibrillation; LA, left atrial; LAA, left atrial appendage; LV, left ventricular