LVADs |
Technology |
Advantages |
Disadvantages |
First generation [18] |
Pulsatile flow |
Mimics natural heart function and immediate support. |
Large size, high infection rate, mechanical failures, and limited durability. |
Second generation [21] |
Continuous flow with axial pumps |
Smaller, lower infection rates, improved survival, better symptom management - Better management of severe heart failure symptoms |
GI bleeding, thrombosis, and infection risk from external power. |
Third generation [22] |
Continuous-flow technology with centrifugal flow pumps |
Longer durability, easier placement, lower stroke risk, and better quality of life. |
Complex, expensive, requiring specialized training, and external power dependence. |