Table 5.
Group comparisons
| Variable | Total AEs | Psychological AEs | Neurological AEs | Autonomic AEs | Other AEs | Sexual AEs | WHODAS total | Cognition | Mobility | Self-care | Getting along | Life activities | Participation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sex | 0.331 (p = 0.002) | 0.330 (p = 0.001) | 0.236 (p = 0.020) | 0.257 (p = 0.013) | 0.206 (p = 0.047) | ||||||||
| Female | Mean 17.667 (SD 10.095) | Mean 6.593 (SD 5.268) | Mean 2.074 (SD 1.941) | Mean 4.630 (SD 3.252) | Mean 4.370 (SD 2.980) | ||||||||
| Male | Mean 12.361 (SD 7.249) | Mean 3.847 (SD 3.266) | Mean 1.264 (SD 1.463) | Mean 3.292 (SD 2.537) | Mean 3.472 (SD 3.076) | ||||||||
| Age, years | 0.231 (p = 0.025) | 0.196 (p = 0.049) | |||||||||||
| 18–49 | Mean 4.366 (SD 3.181) | Mean 2.549 (SD 3.215) | |||||||||||
| < 50 | Mean 3.200 (SD 2.778) | Mean 1.655 (SD 2.696) | |||||||||||
| Educational status | 0.289 (p = 0.004) | ||||||||||||
| No education | Mean 2.109 (SD 1.863) | ||||||||||||
| Education <8 years | Mean 1.225 (SD 1.514) | ||||||||||||
| Marital status | 0.238 (p = 0.039) | 0.272 (p = 0.018) | 0.240 (p = 0.029) | 0.281 (p = 0.012) | |||||||||
| Maiden/divorced | Mean 13.549 (SD 8.391) | Mean 3.462 (SD 2.889) | Mean 1.890 (SD 2.964) | Mean 0.233 (SD 0.205) | |||||||||
| Married | Mean 17.457 (SD 9.820) | Mean 4.886 (SD 3.252) | Mean 2.857 (SD 3.098) | Mean 0.350 (SD 0.245) | |||||||||
| Parental status | 0.201 (p = 0.048) | ||||||||||||
| No children | Mean 1.293 (SD 1.422 | ||||||||||||
| Children | Mean 2.078 (SD 2.018) | ||||||||||||
| Occupational status |
0.231 (p = 0.040) |
0.236 (p = 0.043) |
0.267 (p = 0.021) |
||||||||||
| Unemployed | Mean 1.815 (SD 1.821) | Mean 0.382 (SD 0.187) | Mean 0.386 (SD 0.278) | ||||||||||
| Employed | Mean 1.059 (SD 1.301) | Mean 0.316 (SD 0.195) | Mean 0.251 (SD 0.187) | ||||||||||
| Diagnosis | 0.312 (p = 0.004) | 0.259 (p = 0.017) | 0.285 (p = 0.009) | 0.291 (p = 0.008) | |||||||||
| Schizophrenia-spectrum | Mean 0.330 (SD 0.177) | Mean 0.312 (SD 0.261) | Mean 0.354 (SD 0.241) | Mean 0.419 (SD 0.215) | |||||||||
| Bipolar disorder | Mean 0.431 (SD 0.201) | Mean 0.425 (SD 0.252) | Mean 0.498 (SD 0.288) | Mean 0.531 (SD 0.227) | |||||||||
| Antipsychotic administration | 0.331 (p = 0.002) | 0.259 (p = 0.014) | 0.279 (p = 0.008) | 0.304 (p = 0.004) | 0.272 (p = 0.008) | ||||||||
| Oral | Mean 16.436 (SD 9.176) | Mean 5.564 (SD 4.335) | Mean 4.397 (SD 3.042) | Mean 4.410 (SD 3.085) | Mean 2.487 (SD 3.145) | ||||||||
| LAI | Mean 11.708 (SD 7.792) | Mean 4.146 (SD 4.505) | Mean 3.000 (SD 2.535) | Mean 2.958 (SD 2.813) | Mean 1.625 (SD 2.757) |
AEs adverse effects, LAI long-acting injectable, SD standard deviation, WHODAS World Health Organization Disability Assessment Schedule 2.0