TABLE 1.
Mutant | Bindingc
|
||
---|---|---|---|
p300 | Rb | p21 | |
E1A.928 | +ab | −ab | +b |
E1A.RG2 | −ab | +ab | +b |
E1A.dl26-35 | +ab | +ab | −b |
E1A.dl26-35/928 | +b | −b | −b |
Data obtained from previous work (4,80).
Work described here and unpublished results of E1A interactions with p300 and Rb in HCT116 cells (D. Chattopadhyay).
+, positive for binding to a cellular protein; −, negative for binding to a cellular protein.