Table 2.
Changes in clinical variables from baseline to the end of the 12-week exercise training program
| Characteristics | Baseline | 12 weeks | Change from baseline | P value |
|---|---|---|---|---|
| BMI (kg/m 2 ) | 27.3 ± 3.9 | 27.0 ± 4.1 | 0.3 ± 0.8 | 0.053 |
| SBP (mmHg) | 117.3 ± 17.6 | 115.3 ± 14.8 | -2.0 ± 15.0 | 0.290 |
| DBP (mmHg) | 67.6 ± 12.0 | 68.6 ± 11.8 | 1.0 ± 13.8 | 0.813 |
| Heart rate (bpm) | 67.9 ± 11.5 | 70.5 ± 10.0 | 2.6 ± 11.3 | 0.175 |
| NT-proBNP (pg/mL)* | 720.0 (850.0) | 587.0 (847.3) | -57.0 (266.8) | 0.048 |
| hsCRP (mg/mL)* # | 1.5 (1.4) | 1.2 (1.5) | -0.1 (1.6) | 0.532 |
| 6MWT (m) | 461.2 ± 64.4 | 508.2 ± 65.5 | 47.1 ± 33.4 | < 0.001 |
| VO 2peak (mL/min/Kg)* | 16.4 (5.9) | 19.0 (5.2) | 1.9 (2.6) | 0.002 |
| MLHFQ (points) | ||||
| Physical dimension | 12.0 (16.0) | 4.0 (10.5) | -4.5 (8.0) | 0.009 |
| Emotional dimension | 4.0 (4.0) | 3.0 (8.5) | 0.0 (3.0) | 0.282 |
| Total | 25.0 (26.5) | 13 (30.5) | -9.0 (13.5) | 0.004 |
Data are mean ± standard deviation or *median and interquartile range (IQR). BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; NT-proBNP, N-terminal pro-B-type natriuretic peptide; hsCRP, high-sensitive C-reactive protein; 6MWT, six-minute walk distance test; VO2peak, peak oxygen uptake, and MLHFQ, Minnesota Living with Heart Failure Questionnaire. # n = 15