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. 2024 Aug 12;29(6):1161–1173. doi: 10.1007/s10741-024-10424-8

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Evidence gaps, potential strategies, and ongoing clinical trials to determine optimal strategies for IV diuretic titration during acute decompensated heart failure hospitalizations. There remain many evidence gaps in determining optimal IV diuretic strategies during acute decompensated heart failure hospitalizations to relieve congestion. Several proposed strategies are outlined, with notation of the clinical trials that are currently underway to test these strategies. IV, intravenous; CDT, combination diuretic therapy; WRF, worsening renal function